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Aug 26th, 2013
How are NGS technologies revolutionizing the way we think about healthcare?
Yole Développement, announce its new technology & market analysis: Next Generation Sequencing (NGS).
With this report, Yole Développement proposes you to learn more about the next generation sequencing market. “The Next Generation Sequencing (NGS) market will sharply grow from $2.2B to $4.4B in 2018”, announces Benjamin Roussel, Technology & Market Analyst, Microfluidics & Medical Technologies at Yole Développement. According to him, “This impressive 27% growth will be fueled mainly by huge investments recently made by diagnostic companies associated with the market entry of new products”.
Next Generation Sequencing technologies drive the way toward personalized medicine
Discover the NGS market’s complex organization, splitted in four segments
The market segmentation is a tool used to provide a vision of the market. Based on technical and economic criteria, fours segments have been identified: research, forensics, diagnostics and consumer. Until recently, uses of Next Generation Sequencing tools were limited to research (human whole genome, exome, small genome, targeted, transcriptome, RNA profiling, chIP-Seq, metagenomics…). Nowadays, NGS technologies have found applications mainly in two fields: clinical diagnostics and forensics.
Our investigation describes both current and future applications.
Next Generation Sequencing technologies overview
In April 2003, human genome project was declared complete. This first human genome sequencing took 13 years, mobilized 20000 researchers and cost $3B! Since the early 2000s, sequencing technologies have come a long way from Sanger sequencing (also called 1st generation sequencing) used for the human genome project to the Next Generation Sequencing technologies available today. By sequencing a large number of DNA molecules in parallel after PCR amplification, technology developers have been able to sharply increase machine throughput by a factor of 10, along with a steep price reduction.
The launch of a new detection method based on electrochemical detections was also a huge step forward for the sequencing world.
Today, based on these new technologies, we can sequence the whole human genome in less than three hours with one laboratory technician and a total cost around $1000. Technologies under development are poised to extend the boundaries with a targeted sequencing cost of $100. All technologies currently in use and those under development are presented in our report. Benchmarking is also presented for eight different sequencing applications.
New opportunities arise for cartridge makers
The wide adoption of NGS technology has changed the way NGS suppliers are generating revenue. A shift occurred in the sales mix, moving from instruments to consumables which have a higher gross margin than instruments. This leads to an increase in revenue based on consumable sales. The number of NGS Platforms used worldwide will exploded in the next several years and the run time will continue to decrease. Therefore, the market of NGS consumables will explode.
Yole Développement foresees the NGS Consumables Market growing to $3.1B in 2018, the result of several millions of cartridges being sold each year. For now, glass and silicon are the preferred materials used.
For more information about this report, please click here
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