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Status of the Microfluidics Industry 2017

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Diagnostics, point-of-care, and pharmaceutical research will drive the rapidly-expanding microfluidic products industry to a potential value of $23B by 2022. What will trigger the next growth spurt?

Microfluidic technologies have finally found sweet spots, and there are already credible options for the next upsurge

Microfluidic technologies have been around for a while, but only in the last few years have certain applications started benefiting from microfluidic breakthroughs. First, next-generation sequencing (NGS) found new possibilities enabled by microfluidics; next, in 2014/2015, point-of-care (PoC) testing (especially molecular diagnostics for decentralized use) began reaping microfluidic technologies’ full benefits. These applications are still driving the microfluidics industry’s growth and structure.

In this Status of the Microfluidics Industry report, Yole Développement announces a $2.5B microfluidic device market in 2017 and forecasts a $5.8B market by 2022 (CAGR2017-2022 = 18%). From microfluidic devices like manufactured chips, delivery tools, and dispensers, microfluidic-based products (i.e. diagnostic tests with reagents, vaccines, and cartridges) are provided to end-users, offering numerous possibilities.

The industry’s growth is not surprising, given the high demand from end-users for increasingly automated, integrated, miniaturized solutions. And the microfluidics industry could experience additional growth booms in the next few years. In particular, cancer diagnostics, treatment planning, and follow-up look extremely promising with the increased use of microfluidic technologies at sample preparation level (isolation of circulating tumor cells and DNA in liquid biopsies) and at diagnostics level (molecular diagnostics for oncology for the analysis of these cells and DNA molecules). Organs-on-chips is another microfluidics application with the potential to become a multi-billion-dollar market, enabling more predictive models for drug and compound testing. There is no doubt these emerging applications will drive the market’s continuous growth over the next decade, especially with a myriad of startups emerging and proposing innovative microfluidic solutions to solve today’s and tomorrow’s major issues.

Microfluidics industry products revenue since 2000 Yole report 

Large diagnostics companies are racing to acquire the most promising microfluidic companies. Meanwhile, more and more startups emerge.

Alongside these innovative startups walk the diagnostics giants. They usually propose a few, often successful microfluidic solutions within their immense portfolio: Abbott, Alere, bioMérieux, and Roche have all witnessed growth in at least one of their segments, driven by a microfluidic solution. These success stories result from a solid industry structuration over the past few years: among the numerous companies developing microfluidic-based products, the most promising ones are often acquired by the large diagnostics companies. This was the case for some of molecular diagnostics’ most innovative players: IQuum and BioFire, and more recently Cepheid and Nanosphere, were all acquired by much larger companies. In this context, Yole’s analysts have identified $25B in M&A across the microfluidics industry since 2015. This has created a virtuous circle: the most promising/most successful startups are acquired or become large players themselves, and investors are eager to put money into the ever-growing number of newcomers leveraging microfluidic technologies and know-how.

This report includes a detailed analysis of the $965M invested in microfluidic companies since 2015, as identified by Yole.

Two types of diagnostics player in 2016 Yole report 

The industry’s swift maturation has profoundly impacted the entire supply chain

Microfluidic technologies’ maturation and their increased use within the industry has impacted supply chain structure. Which diagnostics companies are producing their microfluidic devices in-house, which ones are outsourcing, and why? What is the cost of goods sold? Yole’s analysts have investigated these critical points, and their findings are revealed in this report.

Cost pressure is often very high for microfluidic device manufacturers trying to diversify their capabilities in order to generate higher value for their customers. Back-end processing, materials combination and reagent deposition are the points of improvement, rather than manufacturing processes, which have not changed much recently. Depending on the application, different materials are used: polymer, glass, and silicon devices have different properties and are rarely produced by the same players. Low-cost diagnostics disposables are made of polymer, whereas glass and silicon are used in higher-end applications where superior precision and quality are required.

This report furnishes a detailed material mix analysis per application, along with complete supply chain information: who is producing what, and for who?

Supply chain Yole report 

What's new

  • Coverage of all major trends and evolutions in the microfluidics industry and markets
  • Updated market data and forecasts to 2022, in value and units for microfluidic devices and products
  • Analysis of strategic moves (M&A, collaborations, fundraising) since 2015
  • Top microfluidic players/foundries - 2016 rankings
  • Updated information, by microfluidic market segment
  • Review of new, promising applications for microfluidic technologies
  • Current supply chain

Objectives of the Report

This report’s objectives are to:

  • This new Yole Développement report provides a complete analysis of microfluidic device/product applications, markets, and technologies:
    • New major trends and evolutions in the microfluidics industry and markets
    • Analysis of strategic moves since 2015
    • New microfluidics players/foundries - 2016 ranking
    • Updated market data and forecast up to 2022, in value and units for microfluidic devices and products
    • Current supply chain
  • In order to better understand how value is spread across the supply chain, this report covers both the microfluidics device and product markets
  • Market trends and main players are presented for each product category, via an exclusive market segmentation
  • An exhaustive analysis is provided of the materials and manufacturing processes in various microfluidic segments
  • Also offered is a presentation of new, promising applications for microfluidic technologies


Table of contents

Executive Summary         p.8

Introduction p.4

Status of the microfluidics market    p.50

> What’s the next killer application?   
> Supply chain models       
> The future of microfluidic foundries 
> Towards design standards?   
> Two types of diagnostics players 
> New collaborations since 2015 
> Fundraising since 2015 
> Mergers and acquisitions since 2015
> Strategic moves analysis   
> Stock market     
> Patent landscape      
> Razor and razor-blade business model
> Multiplexing     
> Detection methods 

Market segmentation         p.92

Microfluidics market            p.96

> What we got wrong and why   
> Products market (volume, value, dynamics)
> Devices market (value, dynamics) 
> Market shares        
> Pure-fabs vs. The hidden in-house market



























Microfluidic segments description         p.115

> Segment 1: Clinical and veterinary tests  
> Segment 2: Point of care testing    
> Segment 3: Industrial, environmental, agro-food
> Segment 4: Life science research    
> Segment 5: Micro-reactor and flow chemistry
> Segment 6: Analytical devices        
> Segment 7: Drug delivery        
> Segment 8: Accurate dispensing    
> Segment 9: Flow control        

Emerging applications            p.200

> Organs-on-chips                
> Liquid biopsy                
> Electronic cooling            
> Liquid Lenses                

Focus on digital microfluidics            p.212

Microfluidic technologies            p.218

> Materials             
> Material mix analysis        
> Manufacturing processes    

Microfluidics supply chain            p.234

Summary and conclusions             p.242


Companies cited

 10x Genomics
 Advanced Liquid Logic
 Agilent Technologies
 Alfa Laval
 Apogee MEMS
 Applied Biosystems
 ARaymond Life
 Atlas Genetics
 Bartels Mikrotechnik
 Beckman Coulter
 Beijing Genomics Institute
 BioFire Diagnostics
 Boehringer Ingelheim
 Cambridge Consultants
 CapitalBio Technology
 Carbo Analytics
 Daktari Diagnostics
 Denz Biomedical
 DNA Electronics
 Dublin City University
 ETH Zürich
 Etta Healthcare
 Fast-Track Diagnostics
 Focus Diagnostics
 Future Chemistry
 GenMark Diagnostics
 Great Basin Scientific
 HNP Microsystems
 IBM Research
 Ion Torrent

 Johnson & Johnson
 Life Technologies
 Little Things Factory
 Microfluidic ChipShop
 Microglass Chemtech
 Mylife Technologies
 OPKO Diagnostics
 Oxford Nanopore
 Pacific Biosciences
 Pall Corporation
 Rogers Corporation
 Savyon Diagnostics
 Screen Holdings
 Sigma Aldrich
 Silex Microsystems
 Silicon Biosystems
 Scandinavian Micro Biodevices
 Sony DADC
 Sphere Fluidics
 Teledyne Dalsa
 The Lee Company
 Thermo Fisher Scientific
 Tronics Microsystems
 TTP Labtech
 TTP Group
 Two Pore Guys
 Vortex Biosciences
 WaferGen Biosystems
 Weidmann Plastics
 Zephyrus Biosciences
 Zurich Instruments
 and more...


























  • Market evolution and maturation: analyzing the key events from the last two years, including M&A, innovative product launches, fundraising, and collaborations
  • Detailed 2017 - 2022 market data and forecasts by market segment, for the microfluidic device and microfluidic product markets
  • Thorough analysis of the materials and manufacturing processes across different microfluidic segments
  • Comprehensive supply chain analysis