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Status of the Microfluidics Industry 2017
May.2017

microfluidics_industry_products_revenue_since_2000_yole_report
6 490 €

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Description

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Diagnostics, point-of-care, and pharmaceutical research will drive the rapidly-expanding microfluidic products industry to a potential value of $23B by 2022. What will trigger the next growth spurt?

Microfluidic technologies have finally found sweet spots, and there are already credible options for the next upsurge

Microfluidic technologies have been around for a while, but only in the last few years have certain applications started benefiting from microfluidic breakthroughs. First, next-generation sequencing (NGS) found new possibilities enabled by microfluidics; next, in 2014/2015, point-of-care (PoC) testing (especially molecular diagnostics for decentralized use) began reaping microfluidic technologies’ full benefits. These applications are still driving the microfluidics industry’s growth and structure.

In this Status of the Microfluidics Industry report, Yole Développement announces a $2.5B microfluidic device market in 2017 and forecasts a $5.8B market by 2022 (CAGR2017-2022 = 18%). From microfluidic devices like manufactured chips, delivery tools, and dispensers, microfluidic-based products (i.e. diagnostic tests with reagents, vaccines, and cartridges) are provided to end-users, offering numerous possibilities.

The industry’s growth is not surprising, given the high demand from end-users for increasingly automated, integrated, miniaturized solutions. And the microfluidics industry could experience additional growth booms in the next few years. In particular, cancer diagnostics, treatment planning, and follow-up look extremely promising with the increased use of microfluidic technologies at sample preparation level (isolation of circulating tumor cells and DNA in liquid biopsies) and at diagnostics level (molecular diagnostics for oncology for the analysis of these cells and DNA molecules). Organs-on-chisp is another microfluidics application with the potential to become a multi-billion-dollar market, enabling more predictive models for drug and compound testing. There is no doubt these emerging applications will drive the market’s continuous growth over the next decade, especially with a myriad of startups emerging and proposing innovative microfluidic solutions to solve today’s and tomorrow’s major issues.

Microfluidics industry products revenue since 2000 Yole report 

Large diagnostics companies are racing to acquire the most promising microfluidic companies. Meanwhile, more and more startups emerge.

Alongside these innovative startups walk the diagnostics giants. They usually propose a few, often successful microfluidic solutions within their immense portfolio: Abbott, Alere, bioMérieux, and Roche have all witnessed growth in at least one of their segments, driven by a microfluidic solution. These success stories result from a solid industry structuration over the past few years: among the numerous companies developing microfluidic-based products, the most promising ones are often acquired by the large diagnostics companies. This was the case for some of molecular diagnostics’ most innovative players: IQuum and BioFire, and more recently Cepheid and Nanosphere, were all acquired by much larger companies. In this context, Yole’s analysts have identified $25B in M&A across the microfluidics industry since 2015. This has created a virtuous circle: the most promising/most successful startups are acquired or become large players themselves, and investors are eager to put money into the ever-growing number of newcomers leveraging microfluidic technologies and know-how.

This report includes a detailed analysis of the $965M invested in microfluidic companies since 2015, as identified by Yole.

Two types of diagnostics player in 2016 Yole report 

The industry’s swift maturation has profoundly impacted the entire supply chain

Microfluidic technologies’ maturation and their increased use within the industry has impacted supply chain structure. Which diagnostics companies are producing their microfluidic devices in-house, which ones are outsourcing, and why? What is the cost of goods sold? Yole’s analysts have investigated these critical points, and their findings are revealed in this report.

Cost pressure is often very high for microfluidic device manufacturers trying to diversify their capabilities in order to generate higher value for their customers. Back-end processing, materials combination and reagent deposition are the points of improvement, rather than manufacturing processes, which have not changed much recently. Depending on the application, different materials are used: polymer, glass, and silicon devices have different properties and are rarely produced by the same players. Low-cost diagnostics disposables are made of polymer, whereas glass and silicon are used in higher-end applications where superior precision and quality are required.

This report furnishes a detailed material mix analysis per application, along with complete supply chain information: who is producing what, and for who?

Supply chain Yole report 

What's new

  • Coverage of all major trends and evolutions in the microfluidics industry and markets
  • Updated market data and forecasts to 2022, in value and units for microfluidic devices and products
  • Analysis of strategic moves (M&A, collaborations, fundraising) since 2015
  • Top microfluidic players/foundries - 2016 rankings
  • Updated information, by microfluidic market segment
  • Review of new, promising applications for microfluidic technologies
  • Current supply chain


Objectives of the Report

This report’s objectives are to:

  • This new Yole Développement report provides a complete analysis of microfluidic device/product applications, markets, and technologies:
    • New major trends and evolutions in the microfluidics industry and markets
    • Analysis of strategic moves since 2015
    • New microfluidics players/foundries - 2016 ranking
    • Updated market data and forecast up to 2022, in value and units for microfluidic devices and products
    • Current supply chain
  • In order to better understand how value is spread across the supply chain, this report covers both the microfluidics device and product markets
  • Market trends and main players are presented for each product category, via an exclusive market segmentation
  • An exhaustive analysis is provided of the materials and manufacturing processes in various microfluidic segments
  • Also offered is a presentation of new, promising applications for microfluidic technologies

 

Table of contents

Executive Summary         p.8


Introduction p.4


Status of the microfluidics market    p.50


> What’s the next killer application?   
> Supply chain models       
> The future of microfluidic foundries 
> Towards design standards?   
> Two types of diagnostics players 
> New collaborations since 2015 
> Fundraising since 2015 
> Mergers and acquisitions since 2015
> Strategic moves analysis   
> Stock market     
> Patent landscape      
> Razor and razor-blade business model
> Multiplexing     
> Detection methods 

Market segmentation         p.92


Microfluidics market            p.96


> What we got wrong and why   
> Products market (volume, value, dynamics)
> Devices market (value, dynamics) 
> Market shares        
> Pure-fabs vs. The hidden in-house market

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Microfluidic segments description         p.115


> Segment 1: Clinical and veterinary tests  
> Segment 2: Point of care testing    
> Segment 3: Industrial, environmental, agro-food
> Segment 4: Life science research    
> Segment 5: Micro-reactor and flow chemistry
> Segment 6: Analytical devices        
> Segment 7: Drug delivery        
> Segment 8: Accurate dispensing    
> Segment 9: Flow control        

Emerging applications            p.200


> Organs-on-chips                
> Liquid biopsy                
> Electronic cooling            
> Liquid Lenses                

Focus on digital microfluidics            p.212


Microfluidic technologies            p.218


> Materials             
> Material mix analysis        
> Manufacturing processes    

Microfluidics supply chain            p.234


Summary and conclusions             p.242


 

Companies cited

 10x Genomics
 3M
 Abaxis
 Abbott
 Advanced Liquid Logic
 Affymetrix
 AGC
 Agilent Technologies
 Alere
 Alfa Laval
 Aline
 Alza
 Alzet
 Angle
 Apogee MEMS
 Applied Biosystems
 ARaymond Life
 Arrayjet
 A-Star
 Ativa
 Atlas Genetics
 Axxicon
 Axxin
 Azbil
 Baebies
 Bartels Mikrotechnik
 Bayer
 BD
 Beckman Coulter
 Beijing Genomics Institute
 Biocartis
 BioFire Diagnostics
 BioFluidix
 BioMensio
 bioMérieux
 Bio-Rad
 Biotechne
 Boehringer Ingelheim
 Bronkhorst
 Brooks
 Burkert
 Caliper
 Cambridge Consultants
 CapitalBio Technology
 Capsum
 Carbo Analytics
 CDA
 CellSearch
 Celsee
 Cepheid
 Cetoni
 CG.TEC
 Chemtrix
 ChipCare
 Corium
 Corning
 Crospon
 Curiox
 Cytena
 Daktari Diagnostics
 Danaher
 DARPA
 Debiopharm
 Debiotech
 Denz Biomedical
 DiaSorin
 Dimatix
 DNA Electronics
 Dolomite
 Draper
 Dublin City University
 DuPont
 Durect
 EKF
 Eksigent
 Elveflow
 Emulate
 EnablingMNT
 Enplas
 Epigem
 ETH Zürich
 Etta Healthcare
 Fast-Track Diagnostics
 Fluidigm
 Fluigent
 Focus Diagnostics
 Fralock
 Fraunhofer
 Freescale
 Future Chemistry
 GE
 Genalyte
 Genapsys
 GeneFluidics
 GenePOC
 GenMark Diagnostics
 Gilson
 Great Basin Scientific
 Gyros
 Hamilton
 Helvoet
 HNP Microsystems
 Honeywell
 HP
 IBM Research
 IDEX
 Illumina
 IMT
 Imtek
 Invenios
 Invetech
 InZign
 Ion Torrent
 IQuum

 iX-Factory
 Johnson & Johnson
 Kapplex
 Klearia
 Kloehn
 Kumetrix
 Labcyte
 LabSmith
 LeukoDx
 Life Technologies
 LionIX
 Little Things Factory
 Lonza
 Luminex
 LUT
 Malema
 Medimate
 Medspray
 Medtronic
 Menarini
 Micralyne
 microDrop
 Microfluidic ChipShop
 Microglass Chemtech
 microLiquid
 Micronics
 Micronit
 miniFab
 Miroculus
 MyCartis
 Mylife Technologies
 Nabsys
 NanoBiosciences
 Nanocellect
 NanoMR
 NanoPass
 Nanosphere
 NASA
 Norgren
 Nortis
 Omron
 OndaVia
 OPKO Diagnostics
 Ovagene
 Oxford Nanopore
 Pacific Biosciences
 Pall Corporation
 PerkinElmer
 Pfizer
 Philips
 PlanOptik
 POC
 Porter
 PositiveID
 RainDance
 RedShift
 Rheonix
 Roche
 Rogers Corporation
 Rqmicro
 Samsung
 Savyon Diagnostics
 Schlumberger
 Schott
 Scienion
 Sciex
 Screen Holdings
 Sensirion
 SensoDx
 Seyonic
 Shimadzu
 Siemens
 Sigma Aldrich
 Silex Microsystems
 Silicon Biosystems
 Scandinavian Micro Biodevices
 Sony DADC
 Sphere Fluidics
 STMicroelectronics
 Stratec
 Syntics
 Takara
 Takasago
 TDK
 TearLab
 Tecan
 Tecnisco
 Telechem
 Teledyne Dalsa
 Thalesnano
 The Lee Company
 Thermo Fisher Scientific
 ThinXXS
 Translume
 Tronics Microsystems
 TSMC
 TTP Labtech
 TTP Group
 Two Pore Guys
 uFuidix
 Valcor
 Vaxxas
 Vortex Biosciences
 WaferGen Biosystems
 Waters
 Weidmann Plastics
 Xaar
 YMC
 Zephyrus Biosciences
 z-microsystems
 Zoetis
 Zosano
 Zurich Instruments
 and more...

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

KEY FEATURES OF THE REPORT

  • Market evolution and maturation: analyzing the key events from the last two years, including M&A, innovative product launches, fundraising, and collaborations
  • Detailed 2017 - 2022 market data and forecasts by market segment, for the microfluidic device and microfluidic product markets
  • Thorough analysis of the materials and manufacturing processes across different microfluidic segments
  • Comprehensive supply chain analysis